@misc{proefrock_development_and_2005, author={Proefrock, D., Leonhard, P., Ruck, W., Prange, A.}, title={Development and characterisation of a new interface for coupling capillary LC with collision-cell ICP–MS and its application for phosphorylation profiling of tryptic protein digests}, year={2005}, howpublished = {journal article}, doi = {https://doi.org/10.1007/s00216-004-2930-5}, abstract = {Tryptic digests of alpha and beta-casein were investigated as model compounds to demonstrate the applicability of the proposed setup for phosphorylation profiling in protein analysis using quadrupole based collision-cell ICP-MS as phosphorus specific detector. Detection limits for phosphorylated peptides down to the sub pico-mole level have been obtained. As a complementary technique, electrospray ionisation mass spectrometry (ESI-MS/MS) with data base searching has been applied to further characterise the phosphorylated peptides detected.}, note = {Online available at: \url{https://doi.org/10.1007/s00216-004-2930-5} (DOI). Proefrock, D.; Leonhard, P.; Ruck, W.; Prange, A.: Development and characterisation of a new interface for coupling capillary LC with collision-cell ICP–MS and its application for phosphorylation profiling of tryptic protein digests. Analytical and Bioanalytical Chemistry. 2005. vol. 381, no. 1, 194-204. DOI: 10.1007/s00216-004-2930-5}}