@misc{wang_localized_sdf1alpha_2010, author={Wang, W., Li, W., Ong, L.-L., Furlani, D., Kaminski, A., Liebold, A., Luetzow, K., Lendlein, A., Wang, J., Li, R.-K., Steinhoff, G., Ma, N.}, title={Localized SDF-1alpha gene release mediated by collagen substrate induces CD117+ stem cell homing}, year={2010}, howpublished = {journal article}, doi = {https://doi.org/10.1111/j.1582-4934.2008.00624.x}, abstract = {Results: The optimized parameters for GAC were DNA dosage 10μg/cm2, molar ratio of PEI nitrogen in primary amine to DNA phosphate (N/P ratio) 4 and mass ratio of collagen to DNA (C/D ratio) 1.0. It kept cell viability above 75% and transfection efficiency around 5.8 × 105 RLU/mg protein. GAC allowed the sustained gene release up to 60 days. GAC mediated SDF-1α gene release induced migration and homing of CD117+ stem cells in vitro and in vivo significantly, and the inflammation of GAC reduced significantly two weeks after transplantation. GAC is a promising stem cell based therapeutic strategy for regenerative medicine.}, note = {Online available at: \url{https://doi.org/10.1111/j.1582-4934.2008.00624.x} (DOI). Wang, W.; Li, W.; Ong, L.; Furlani, D.; Kaminski, A.; Liebold, A.; Luetzow, K.; Lendlein, A.; Wang, J.; Li, R.; Steinhoff, G.; Ma, N.: Localized SDF-1alpha gene release mediated by collagen substrate induces CD117+ stem cell homing. Journal of Cellular and Molecular Medicine. 2010. vol. 14, no. 1-2, 392-402. DOI: 10.1111/j.1582-4934.2008.00624.x}}