@misc{gordin_surface_characterization_2012, 
author={Gordin, D.M., Gloriant, T., Chane-Pane, V., Busardo, D., Mitran, V., Hoeche, D., Vasilescu, C., Drob, S.I., Cimpean, A.},
title={Surface characterization and biocompatibility of titanium alloys implanted with nitrogen by Hardion+ technology},
year={2012},
howpublished = {journal article},
doi = {https://doi.org/10.1007/s10856-012-4750-z},
abstract = {In this study, the new Hardion+ micro-implanter technology was used to modify surface properties of biomedical pure titanium (CP-Ti) and Ti–6Al–4V ELI alloy by implantation of nitrogen ions. This process is based on the use of an electron cyclotron resonance ion source to produce a multienergetic ion beam from multicharged ions. After implantation, surface analysis methods revealed the formation of titanium nitride (TiN) on the substrate surfaces. An increase in superficial hardness and a significant reduction of friction coefficient were observed for both materials when compared to non-implanted samples. Better corrosion resistance and a significant decrease in ion release rates were observed for N-implanted biomaterials due to the formation of the protective TiN layer on their surfaces. In vitro tests performed on human fetal osteoblasts indicated that the cytocompatibility of N-implanted CP-Ti and Ti–6Al–4V alloy was enhanced in comparison to that of the corresponding non treated samples. Consequently, Hardion+ implantation technique can provide titanium alloys with better qualities in terms of corrosion resistance, cell proliferation, adhesion and viability.},
note = {Online available at: \url{https://doi.org/10.1007/s10856-012-4750-z} (DOI). Gordin, D.; Gloriant, T.; Chane-Pane, V.; Busardo, D.; Mitran, V.; Hoeche, D.; Vasilescu, C.; Drob, S.; Cimpean, A.: Surface characterization and biocompatibility of titanium alloys implanted with nitrogen by Hardion+ technology. Journal of Materials Science: Materials in Medicine. 2012. vol. 23, no. 12, 2953-2966. DOI: 10.1007/s10856-012-4750-z}}