SANS contrast variation study of magnetoferritin structure at various iron loading

Melnikova, L.; Petrenko, V.I.; Avdeev, M.V.; Ivankov, O.I.; Bulavin, L.A.; Haramus, V.M.; Almasy, L.; Mitroova, Z.; Kopcansky, P.

Journalpaper

SANS contrast variation study of magnetoferritin structure at various iron loading

Abstract

Magnetoferritin, a synthetic derivate of iron storage protein – ferritin, has been synthesized with different iron oxide loading values. Small-angle neutron scattering experiments were applied to study the structure of magnetoferritin solutions using contrast variation method by varying the light to heavy water ratio of the solvent. Higher iron loading leads to increase of the neutron scattering length density of magnetoferritin and also to the increase of the polydispersity of complexes. The formation of the magnetic core and the variation of the protein shell structure upon iron loading are concluded.

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URL: https://publications.hereon.de/id/32558/
Authors:Melnikova, L., Petrenko, V.I., Avdeev, M.V., Ivankov, O.I., Bulavin, L.A., Haramus, V.M., Almasy, L., Mitroova, Z., Kopcansky, P.
Year:2015
In: Journal of Magnetism and Magnetic Materials
Volume:377
Pages:77 - 80
Publisher:Elsevier
Type:Journalpaper
ISSN: 0304-8853
Cite as: Melnikova, L.; Petrenko, V.I.; Avdeev, M.V.; Ivankov, O.I.; Bulavin, L.A.; Haramus, V.M.; Almasy, L.; Mitroova, Z.; Kopcansky, P.: SANS contrast variation study of magnetoferritin structure at various iron loading. In: Journal of Magnetism and Magnetic Materials. Vol. 377 (2015) 77 - 80. (DOI: 10.1016/j.jmmm.2014.10.085)