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Construction and Characterization of a Novel Sustained-Release Delivery System for Hydrophobic Pesticides Using Biodegradable Polydopamine-Based Microcapsules

Abstract

Microcapsule formulations have been highly desirable and widely developed for effective utilization of pesticides and environmental pollution reduction. However, commercial and traditional microcapsule formulations of λ-cyhalothrin (LC) were prepared by complicated synthesis procedures and thereby specific organic solvents were needed. In this work, LC was encapsulated into versatile, robust, and biodegradable polydopamine (PDA) microcapsules by self-polymerization of dopamine. LC-loaded PDA microcapsules were characterized by transmission electron microscopy (TEM), small-angle X-ray scattering (SAXS), and thermogravimetric analysis measurements (TGA). LC-loaded PDA microcapsules have uniform morphology with nanoscale, decent LC loading content (>50.0% w/w), and good physicochemical stability and sustained release properties. The bioassay against housefly (Musca domestica) showed that the bioactivity and long-term efficiency of LC-loaded PDA microcapsules was superior to that of the commercial formulation. All of these results demonstrated that LC-loaded PDA microcapsules could be applied as a commercial LC microcapsule formulation with fewer environmental side effects and higher effective delivery.
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