Journalpaper

Influence of synthesis temperature on structural and magnetic properties of magnetoferritin

Abstract

The variation of synthesis temperature made it possible to produce artificial ferritins possessing different structural and magnetic properties, size distribution, and colloidal stability. The effect of synthesis temperature on the core structure and stability of protein shell was investigated using small-angle neutron scattering, small-angle X-ray scattering, SQUID magnetometry, dynamic light scattering, and zeta potential measurements. The optimal temperature was established for the synthesis of artificial ferritin suitable for biomedical imaging applications at ∼60 °C, which is close to the protein denaturation temperature.
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